WebMay 31, 2024 · The surface of the podocyte plasma membrane contains depressions 20–30 nm in size that are reminiscent of intramembrane particles; their nature is currently unknown. The podocyte filtration barrier appears as a ladder-like structure at the interface between adjacent foot processes with “slit diaphragm” structures overlaying the basal lamina [3]. Podocytes are found lining the Bowman's capsules in the nephrons of the kidney. The foot processes known as pedicels that extend from the podocytes wrap themselves around the capillaries of the glomerulus to form the filtration slits. The pedicels increase the surface area of the cells enabling efficient ultrafiltration. Podocytes secrete and maintain the basement membrane.

Filtration Flashcards Quizlet

Webpodocytes underwent propagation (Figure 1F) and when incubated at 37uC displayed growth arrest with a typical arborized pattern of foot process extensions (Figure 1G). … WebPodocytes have a cell body with numerous primary, secondary and tertiary extensions, called foot processes. Adjacent foot processes are interconnected by slit diaphragms, … csc and csci

WT1 is a key regulator of podocyte function: reduced ... - PubMed

Webpod·o·cyte. The modified epithelial cell of the visceral layer of glomerular capsule in the renal corpuscle, attached to the outer surface of the glomerular capillary basement … WebAug 4, 2011 · Podocytes are highly specialized and terminally differentiated epithelial cells of mesenchymal origin that are critically required for maintenance of the glomerular filtration barrier (Pavenstädt et al. 2003).Podocytes form cytoplasmic extensions called foot processes which attach to the outer surface of the glomerular basement membrane and … WebSep 3, 2013 · Podocytes must establish and maintain a very delicate 3D cell shape that is characterized by a tremendous extension of the apical membrane and a complex basal … csc and cph license