Circwhsc1
WebDec 1, 2024 · CircWHSC1 overexpressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR‐646, which was confirmed using … WebCompared with vector transfected group, subcutaneous injection of circWHSC1-overexpressed cells showed a more rapid rate of growth and larger tumor volume (a, b). The expression of circWHSC1 was ...
Circwhsc1
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WebDec 1, 2024 · The role of circWHSC1 in vivo was verified by tumor xenograft assay. The relationship between miR-212-5p and circWHSC1 or AKT3 was verified via dual-luciferase reporter and RNA pull-down assays. CircWHSC1 was upregulated in BC tissues and cells. Also, circWHSC1 could discriminate BC tissues and paracancerous normal tissues. WebDec 1, 2024 · CircWHSC1 overexpressed nude mice showed increased tumorigenicity. Bioinformatics predicted that circWHSC1 binds to miR‐646, which was confirmed using luciferase reporter gene assays.
WebOct 30, 2024 · Silence of circWHSC1 exerted the opposite effects. Additionally, circWHSC1 could sponge miR-145 and miR-1182 and up-regulate the expression of downstream targets MUC1 and hTERT. Exosomal circWHSC1 can be transferred to peritoneal mesothelial cells and promotes peritoneal dissemination. Conclusions WebJul 27, 2024 · CircWHSC1 is an independent indicator of poor prognosis in NSCLC patients, and functions as a ceRNA of miR-296-3p to up-regulate AKT3, consequently promotes NSCLC cell growth and metastasis. Targeting circWHSC1 might be a prospective strategy for diagnosis, therapeutics, and prognosis of NSCLC.
WebJan 5, 2024 · CircWHSC1 is a novel circRNA that accelerates ovarian cancer progression. Nevertheless, the function of circWHSC1 in regulating breast cancer (BC) is elusive. … Webboth circWHSC1 overexpressed and down-regulated cell lines were further selected with 2 μg/mL puromycin. The sequences of circWHSC1 and shRNA can be found in Additional file 1:TableS3. MTT assay The circWHSC1 overexpressed and down-regulated cells with control group were counted and seeded in 96-well plates. 0h, 24h, 48h and 72h after …
WebMar 9, 2024 · CircWHSC1 regulates malignancy and glycolysis by the miR-212-5p/AKT3 pathway in triple-negative breast cancer. Inhibition of lncRNA TCONS_00077866 Ameliorates the High Stearic Acid Diet-Induced Mouse Pancreatic beta-Cell Inflammatory Response by Increasing miR-297b-5p to Downregulate SAA3 Expression.
WebNov 3, 2006 · We found that circWhsc1 was enriched in neonatal mouse hearts, particularly in cardiac ECs, and was further upregulated both in ECs and EC-derived EVs under hypoxic conditions. When cocultured with hypoxia-preconditioned neonatal ECs or their secreted EVs, both neonatal and adult CMs exhibited an increased proliferation rate and G2/M … dike iowa weather radarWebIntroduction. Non-small cell lung cancer (NSCLC) takes up 80% of all lung cancer cases and is the most common type of human lung cancer. 1 Although surgery, radiotherapy, and chemotherapy have great progress, the 5-year survival rate of NSCLC patients is still less than 19% due to relapse and drug resistance, and the lack of sensitive and efficient early … fort davis tx rentalsWebDec 1, 2024 · CircWHSC1 [170] and circPUM1 [77] were reported to not only promote EOC cell proliferation, migration and invasion by sponging miRNAs but also act on the peritoneum in an exosome-dependent manner ... fort davis tx webcamWebZestimate® Home Value: $326,700. 401 Wych Cir, Crestview, FL is a single family home that contains 1,802 sq ft and was built in 2009. It contains 3 bedrooms and 2 bathrooms. … dike maintenance act bcWebExosomal circWHSC1 can be transferred to peritoneal mesothelial cells and promotes peritoneal dissemination. Conclusions Our study demonstrates the highly expressed circWHSC1 in ovarian cancer promotes tumorigenesis by sponging miR-145 and miR-1182, and its exosome forms induce tumor metastasis through acting on peritoneal mesothelium. fort davis tx to el paso txWebSee sales history and home details for 401 Wych Cir, Crestview, FL 32536, a 3 bed, 2 bath, 1,800 Sq. Ft. single family home built in 2009 that was last sold on 06/25/2009. fort davis washington dcWebJun 25, 2009 · 401 Wych Cir, Crestview, FL 32536 is a 3 bedroom, 2 bathroom, 1,802 sqft single-family home built in 2009. This property is not currently available for sale. 401 … dike iowa post office hours